Biology Services
Biology Overview
Our biology services encompass an integrated approach to drug discovery services, combining our expertise in both in vitro biology and in vivo biology methodologies. Our aim is to provide accurate, high-quality services within a framework of competitive timelines, supporting advanced small molecule R&D and integrated drug discovery.
In Vitro Biology
Provide cutting-edge screening technologies and assay development capabilities to fast-track the identification and optimization of potential therapeutic agents within drug discovery programs.
In Vivo Biology
Designed to deliver suitable animal models to elucidate efficacy and mechanism of action (MoA) of drug candidates, strengthening outcomes across preclinical development. .
We offer our clients a robust, multidisciplinary approach to overcoming the challenges of drug development solutions and accelerating the journey from concept to clinic within a comprehensive CRDMO services framework.
In Vitro Biology
Our In Vitro Biology services are designed to streamline the drug discovery process through high-throughput screening and assay development.
Assay Development
We specialize in developing and optimizing biochemical and cell-based assays, including ex vivo (blood and tissue based assays) andWe specialize in developing and optimizing biochemical and cell-based assays, including ex vivo (blood and tissue-based assays) and hydrolysis product identification with LCMS/MS readouts. Our services cover various therapeutic areas, utilizing advanced technologies like nano BRET, alpha LISA, HTRF, and fluorescence polarization. We also offer cancer cell lines and cell line development services through CRISPR, supporting cutting-edge biopharmaceutical research.
High-Throughput Screening
Our advanced automated systems expedite high-throughput screening across vast chemical libraries, ensuring precision and rapid identification of promising candidates. Each HTS campaign is rigorously validated with optimizations and QC parameters for consistent, accurate results in drug discovery services.
Mechanism of Action Studies
Our in vitro analyses reveal drug mechanisms by identifying molecular targets, signaling pathways, and off-target effects, using RTqPCR, western blot, and tailor-made assays for comprehensive insights into small molecule drug discovery.
In Vivo Biology
In Vivo Biology services encompass a broad spectrum of capabilities designed to translate in vitro discoveries into relevant animal models, enabling efficient preclinical development within pharmaceutical research and development.
Our end-to-end services include:
Animal Model Selection
We provide a range of animal disease models for oncology, metabolic disorders, inflammation, and pain. Our offerings include xenograft and syngeneic models in oncology. All animals are routinely validated for genotypic traits, with various rodent types available to meet specific study needs in drug discovery programs.
Preclinical Study Design and Execution
Our team specializes in designing and conducting preclinical studies to investigate the pharmacokinetics, pharmacodynamics, and overall efficacy of drug candidates. We are also adept at performing comprehensive toxicology evaluations to determine safety profiles within CRDMO services.
In Vivo Pharmacology
Through meticulous in vivo pharmacological assessments, we explore the distribution, metabolism, excretion, and disease-modifying effects of drug candidates, providing invaluable insights into their therapeutic potential across small molecule R&D.
Toxicology Testing
Our toxicology testing services encompass both acute and chronic evaluations, aiming to uncover any potential long-term side effects, thus ensuring the safety of drug candidates in drug development solutions.
Infrastructure and Instrumentation
