| APIXABAN |
 |
503612-47-3 |
Anticoagulant |
Pd-catalyzed cross-coupling
Amide bond formation
Heterocyclic synthesis |
| BEMPEDOIC ACID |
 |
738606-46-7 |
Hypercholesterolemia |
Multi-step alkylation
Carboxylic acid chemistry |
| CETIRIZINE DIHYDROCHLORIDE |
 |
83881-52-1 |
Antihistamine |
Reductive amination
N-alkylation
HCl salt formation |
| DONEPEZIL HYDROCHLORIDE |
 |
120011-70-3 |
Antialzheimer |
Wittig reaction
Hydrogenation
HCl salt formation |
| DONEPEZIL HYDROCHLORIDE MONOHYDRATE |
 |
884740-09-4 |
Antialzheimer |
Wittig reaction
Hydrogenation
HCl salt formation (monohydrate) |
| DOXAZOSIN MESYLATE |
 |
77883-43-3 |
Antihypertension |
Amide coupling
Piperazine chemistry
Mesylate salt formation |
| EMPAGLIFLOZIN |
 |
864070-44-0 |
Antidiabetic |
Glycosylation reaction
C-aryl glucoside synthesis
Chiral resolution |
| ESCITALOPRAM OXALATE |
 |
219861-08-2 |
Antidepressant |
Asymmetric synthesis
Chiral resolution
Oxalate salt formation |
| ETORICOXIB |
 |
202409-33-4 |
Non-steroidal anti-inflammatory |
Suzuki coupling
Heterocycle formation
Oxidation chemistry |
| FAVIPIRAVIR |
 |
259793-96-9 |
Antiviral |
Fluorination
Pyrazine synthesis
Amide chemistry |
| HYDROXYCHLOROQUINE SULFATE |
 |
747-36-4 |
Auto Immune |
Nucleophilic aromatic substitution
Sulfate salt formation |
| LACOSAMIDE |
 |
175481-36-4 |
Antiepileptic |
Chiral amino acid chemistry
Amide coupling
O-methylation |
| LEVOCETIRIZINE DIHYDROCHLORIDE |
 |
130018-77-8 |
Antiinflammatory |
Chiral resolution
N-alkylation
DiHCl salt formation |
| MIRABEGRON |
 |
223673-61-8 |
Overactive bladder (OAB) |
Thiazole synthesis
Reductive amination
Urea formation |
| MONTELUKAST SODIUM |
 |
151767-02-1 |
Antiinflammatory / Asthma |
Multi-step synthesis
Thioether chemistry
Sodium salt formation |
| OLANZAPINE |
 |
132539-06-1 |
Antipsychotic / Schizophrenia |
Thienobenzodiazepine synthesis
Methylation
Heterocyclic chemistry |
| ONDANSETRON HYDROCHLORIDE DIHYDRATE |
 |
103639-04-9 |
Antiemetic |
Carbazolone synthesis
N-alkylation
HCl salt formation (dihydrate) |
| RALOXIFENE HYDROCHLORIDE |
 |
82640-04-8 |
Osteoporosis |
Benzothiophene synthesis
Friedel-Crafts acylation
HCl salt formation |
| RESMETIROM |
 |
920509-32-6 |
Fatty liver |
Diaryl ether synthesis
Trifluoromethylation
Amide coupling |
| RIVAROXABAN |
 |
366789-02-8 |
Anticoagulant |
Morpholinone synthesis
Chloroaniline chemistry
Oxazolidinone formation |
| ROSUVASTATIN CALCIUM |
 |
147098-20-2 |
Lipid lowering |
Wittig/HWE olefination
Chiral synthesis
Calcium salt formation |
| SITAGLIPTIN HYDROCHLORIDE |
 |
486459-71-6 |
Antidiabetic |
Asymmetric hydrogenation
Triazole formation
HCl salt formation |
| SITAGLIPTIN PHOSPHATE |
 |
654671-77-9 |
Antidiabetic |
Asymmetric hydrogenation
Triazole formation
Phosphate salt formation |
| SUMATRIPTAN SUCCINATE |
 |
103628-46-2 |
Migraine |
Indole synthesis
Sulfonamide formation
Succinate salt formation |
| TAMSULOSIN HYDROCHLORIDE |
 |
106463-17-6 |
Benign Prostatic Hyperplasia / BPH |
Chiral resolution
Sulfonamide chemistry
HCl salt formation |
| TERAZOSIN HYDROCHLORIDE DIHYDRATE |
 |
70024-40-7 |
Hypertension / Benign Prostatic Hyperplasia |
Quinazoline synthesis
Piperazine chemistry
HCl salt (dihydrate) |
| TOFACITINIB |
 |
477600-75-2 |
Autoimmune / Inflammatory |
Pyrrolo[2,3-d]pyrimidine synthesis
Chiral amine chemistry
Nitrile group installation |
| TOPIRAMATE |
 |
97240-79-4 |
Anticonvulsant |
Fructose-derived synthesis
Sulfamate formation
Acetonide protection |
| VILDAGLIPTIN |
 |
274901-16-5 |
Antidiabetic |
Pyrrolidine synthesis
Cyano group introduction
Amide coupling |
| ZOLPIDEM TARTRATE |
 |
99294-93-6 |
Sedative-hypnotic / Insomnia |
Imidazopyridine synthesis
Amide coupling
Tartrate salt formation |
| DAPAGLIFLOZIN PROPANEDIOL |
 |
960404-48-2 |
Antidiabetic |
C–C Glycosidic Bond Formation, Grignard / Organolithium Addition, Selective Protection & Deprotection of Hydroxyl Group |
| LEVETIRACETAM |
 |
102767-28-2 |
Epilepsy Treatment |
Amide Bond Formation, Chiral Resolution / Asymmetric Synthesis |
| LINAGLIPTIN |
 |
668270-12-0 |
Antidiabetic |
N-Alkylation / N-Arylation, Cross-Coupling Reactions (e.g., Suzuki / Buchwald–Hartwig) |
| ELTROMBOPAG OLAMINE |
 |
496775-62-3 |
Thrombopoietin receptor |
Diazotization Reaction, Amide Bond Formation, Olamine Salt Formation |
| DEXLANSOPRAZOLE POWDER |
 |
138530-94-6 |
GERD |
Chiral sulfoxide synthesis
Benzimidazole chemistry
Asymmetric oxidation |
| FINERENONE |
 |
1050477-28-5 |
CKD with type-2 diabetes |
Dihydronaphthyridinone synthesis
Chiral amine coupling
Amide bond formation |
| FEXUPRAZAN |
 |
1902954-60-2 |
GERD |
Benzimidazole synthesis
Sulfonylmethyl chemistry
Methoxylation |
| MIROGABALIN BESYLATE |
 |
1138245-21-2 |
Peripheral neuropathic pain / Diabetic neuropathy |
Cyclopentane synthesis
GABA analog chemistry
Besylate salt formation |
| RIMEGEPANT |
 |
1289023-67-1 |
Migraine |
Bridged bicyclic synthesis
CGRP antagonist chemistry
Amide coupling |
| SOLIFENACIN SUCCINATE |
 |
242478-38-2 |
Overactive bladder (OAB) |
Chiral quinuclidine synthesis
Carbamate formation
Succinate salt |
| SPARSENTAN |
 |
254740-64-2 |
Primary immunoglobulin nephropathy |
Sulfonamide chemistry
Pentanoyl group
Endothelin/AT1 dual antagonist |
| SUZETRIGINE |
 |
2649467-58-1 |
Pain Management - Non-opioid analgesic |
Isoxazole synthesis
Benzoxazolinone chemistry
Nav1.8 inhibitor synthesis |
| TAVABOROLE |
 |
174671-46-6 |
Atopic Dermatitis / Anti-Fungal |
Boron chemistry
Cyclic boronate ester
Antifungal synthesis |
| TEGOPRAZAN |
 |
942195-55-3 |
GERD |
Potassium channel blocker
Pyrrole synthesis
Amide coupling |
| UBROGEPANT |
 |
1374248-77-7 |
Migraine |
Bridged bicyclic synthesis
CGRP antagonist
Trifluoromethyl installation |
| UPADACITINIB |
 |
1310726-60-3 |
Rheumatoid Arthritis |
Chiral pyrrolidine synthesis
JAK inhibitor chemistry
Macrocyclization |
| VIBEGRON |
 |
1190389-15-1 |
Anti-Epileptic |
Oxetane synthesis
Beta-3 agonist chemistry
Amide coupling |
| ZAVEGEPANT |
 |
1337918-83-8 |
Migraine |
Bridged bicyclic core
Difluoromethyl installation |
